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As organisms get larger their surface-area-to-volume ratio falls, so simple diffusion across the body surface is no longer enough and specialised exchange surfaces and mass-transport systems evolve. This chapter covers gas exchange in animals and plants, digestion and absorption, the transport of oxygen by haemoglobin, the heart and cardiac cycle, and the movement of water and sugars through plants.
6 sections~19 min reading time3 competenciesLevel Foundation 1 · Standard 2 · Advanced 3
basic level
AS-Level covers surface area to volume ratio, exchange surfaces, gas exchange, digestion and absorption, and mass transport in animals and plants.
higher level
The full A-Level expects quantitative interpretation of dissociation curves and cardiac pressure traces and evaluation of the transport theories.
Reading depth: In depth
Text size: Standard
SA:V ratio against size
Surface area to volume ratio
The ratio falls as size () rises; small organisms have a large SA:V and can exchange across the body surface.
Fick's law (proportionality)
Explains why exchange surfaces are large, thin and kept at a steep gradient.
Calculate the surface-area-to-volume ratio of a cube of side 1 cm and a cube of side 3 cm, and comment.
SA = cm2; V = cm3; ratio = 6:1.
SA = cm2; V = cm3; ratio = .
The larger cube has a much smaller SA:V ratio, so diffusion across the surface cannot supply its greater volume - a specialised exchange surface is needed.
Result: 6:1 for the small cube and 2:1 for the large cube.
Typical mistakes
Active revision
Calculate the SA:V ratio of a cube of side 2 mm and of side 4 mm, and use them to explain why a large organism needs a specialised gas-exchange surface.
Active recall
Recall the key points — then reveal.
Sources: GCE AS and A level subject content for the sciences (Department for Education) · AQA A-level Biology 7402 specification (AQA)
Counter-current flow in a fish gill
Compare oxygen uptake in counter-current and concurrent gill systems, explaining the difference in terms of concentration gradients.
Water and blood flow the same way; their oxygen concentrations equalise about halfway along, after which no net diffusion occurs, so the blood leaves only about 50% saturated.
Water and blood flow in opposite directions, so at every point the water still has a higher oxygen concentration than the adjacent blood - a gradient exists along the entire lamella.
Diffusion of oxygen into the blood continues all along the lamella, so the blood can reach a much higher saturation (around 80-90%).
Result: Counter-current flow maintains a gradient along the whole lamella, giving far higher oxygen uptake.
Typical mistakes
Active revision
Explain why a fish gill using a counter-current system can absorb more oxygen from the water than one in which water and blood flow in the same direction.
Active recall
Recall the key points — then reveal.
Sources: GCE AS and A level subject content for the sciences (Department for Education) · AQA A-level Biology 7402 specification (AQA)
Digestion of starch to glucose
Describe, in sequence, how sodium ions enable glucose to be absorbed against its concentration gradient in the ileum.
Sodium ions are actively transported (using ATP) from the epithelial cell into the blood, lowering the sodium concentration inside the cell.
Sodium diffuses from the gut lumen into the cell through a co-transporter protein, and glucose is carried in with it, even against the glucose gradient.
Glucose then moves from the cell into the blood by facilitated diffusion down its gradient.
Result: A sodium gradient set up by active transport drives glucose uptake by co-transport.
Typical mistakes
Active revision
Explain how a molecule of glucose in the lumen of the ileum ends up in the blood, referring to the role of sodium ions and ATP.
Active recall
Recall the key points — then reveal.
Sources: GCE AS and A level subject content for the sciences (Department for Education) · AQA A-level Biology 7402 specification (AQA)
Oxygen dissociation curves
Using the adult curve, at a tissue partial pressure of oxygen where the saturation is 40% and a lung partial pressure where it is 96%, calculate the percentage of oxygen unloaded between the lungs and the tissues.
In the lungs the haemoglobin is 96% saturated; in the tissues it falls to 40%.
Percentage unloaded = 96 - 40.
56% of the haemoglobin's oxygen capacity is released to the tissues - the steep middle of the curve makes this large release possible for a modest fall in partial pressure.
Result: 56% of the oxygen carried is unloaded to the tissues.
Typical mistakes
Active revision
Fetal haemoglobin has a dissociation curve to the left of the mother's. Explain how this allows the fetus to obtain oxygen from the maternal blood at the placenta.
Active recall
Recall the key points — then reveal.
Sources: GCE AS and A level subject content for the sciences (Department for Education) · AQA A-level Biology 7402 specification (AQA)
The cardiac cycle sequence
Cardiac output
Volume of blood pumped by one ventricle per minute; both factors rise during exercise.
Pressure changes in the left heart
At rest a person has a heart rate of 72 beats per minute and a stroke volume of 70 cm3. Calculate their cardiac output in cm3 min-1 and in dm3 min-1.
Cardiac output = heart rate x stroke volume = .
(since 1 dm3 = 1000 cm3).
Result: Cardiac output = 5040 cm3 min-1 = 5.04 dm3 min-1.
Typical mistakes
Active revision
A person has a stroke volume of 75 cm3 and a heart rate of 68 beats per minute. Calculate their cardiac output in dm3 per minute.
Active recall
Recall the key points — then reveal.
Sources: GCE AS and A level subject content for the sciences (Department for Education) · AQA A-level Biology 7402 specification (AQA)
A potometer
Potometer rate
is the radius of the capillary tube; multiplying the distance the bubble moves by the cross-sectional area gives a volume.
In a potometer the air bubble moves 60 mm in 5 minutes. The capillary tube has a radius of 0.5 mm. Calculate the rate of water uptake in mm3 min-1.
Area = mm2.
Volume = distance x area = mm3.
Rate = .
Result: About 9.4 mm3 min-1.
Typical mistakes
Active revision
Explain how an increase in wind speed and a decrease in humidity would each affect the rate of transpiration measured by a potometer.
Active recall
Recall the key points — then reveal.
Sources: GCE AS and A level subject content for the sciences (Department for Education) · AQA A-level Biology 7402 specification (AQA)
References & sources
Department for Education